CMap Candidate Details

Structure:
CMap ID: C04369
Pert ID: BRD-K06221026
Compound Name: DUP-697
Targets: PTGS2
MoA: Cyclooxygenase inhibitor
SMILES: CS(=O)(=O)c1ccc(cc1)-c1cc(Br)sc1-c1ccc(F)cc1
InchiKey: AJFTZWGGHJXZOB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4188 BRD-K06221026 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4347 BRD-K06221026 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.75 0.06
22089 BRD-K06221026 A375 10 uM 6 h 0.23 0.96 0.07 0.26 0.91 0.23
22109 BRD-K06221026 A549 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.32 1.71
22973 BRD-K06221026 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23280 BRD-K06221026 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23696 BRD-K06221026 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23961 BRD-K06221026 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24279 BRD-K06221026 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44831 BRD-K06221026 ASC 10 uM 24 h -0.25 -1.05 0.24 0.24 0.85 0.15
45946 BRD-K06221026 NPC 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).