CMap Candidate Details

Structure:
CMap ID: C00437
Pert ID: BRD-A17453586
Compound Name: MDL-72832
Targets: HTR1A
MoA: Serotonin receptor agonist
SMILES: O=C1CC2(CCCC2)CC(=O)N1CCCCNCC1COc2ccccc2O1
InchiKey: HCVRCHQFYYZPHT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2958 BRD-A17453586 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3309 BRD-A17453586 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.3
3428 BRD-A17453586 PC3 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.48
3667 BRD-A17453586 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41650 BRD-A17453586 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41999 BRD-A17453586 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42181 BRD-A17453586 ASC 10 uM 24 h 0.0 0.0 0.0 0.21 0.73 0.03
42526 BRD-A17453586 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.28 1.0 0.42
42834 BRD-A17453586 HT29 10 uM 6 h 0.0 0.0 0.0 -0.19 -0.64 0.01
43253 BRD-A17453586 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43381 BRD-A17453586 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43698 BRD-A17453586 PHH 10 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
43995 BRD-A17453586 SKB 10 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.37
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).