CMap Candidate Details

Structure:
CMap ID: C00438
Pert ID: BRD-A17462676
Compound Name: bambuterol
Targets: ADRB2
MoA: Adrenergic receptor agonist
SMILES: CN(C)C(=O)Oc1cc(OC(=O)N(C)C)cc(c1)C(O)CNC(C)(C)C
InchiKey: ANZXOIAKUNOVQU-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91079 BRD-A17462676 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
120248 BRD-A17462676 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120286 BRD-A17462676 A549 0.37 uM 24 h 0.0 0.0 0.0 -0.32 -1.06 0.73
120321 BRD-A17462676 HA1E 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120362 BRD-A17462676 HELA 0.04 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
120381 BRD-A17462676 HT29 0.125 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.15
120411 BRD-A17462676 MCF??7.00 0.04 uM 24 h -0.22 -0.9 0.04 0.0 0.0 0.0
120443 BRD-A17462676 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.56
120482 BRD-A17462676 YAPC 0.04 uM 24 h -0.26 -1.06 0.26 -0.25 -0.86 0.2
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).