CMap Candidate Details

Structure:
CMap ID: C00439
Pert ID: BRD-A17535965
Compound Name: gelsemine
Targets: GLRA3
MoA: Glycine receptor antagonist; Acetylcholine receptor antagonist
SMILES: CN1C[C@@]2(C=C)C3CC4OC[C@@H]3[C@@H]1[C@H]2[C@@]45C(=O)Nc6ccccc65
InchiKey: NFYYATWFXNPTRM-KMXOBDGGSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6829 BRD-A17535965 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6918 BRD-A17535965 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7379 BRD-A17535965 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.7 0.03
7749 BRD-A17535965 HT29 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.15
8150 BRD-A17535965 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8295 BRD-A17535965 PC3 10 uM 24 h 0.0 0.0 0.0 0.33 1.18 0.97
8554 BRD-A17535965 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).