CMap Candidate Details

Structure:
CMap ID: C00442
Pert ID: BRD-A17655518
Compound Name: ibuprofen
Targets: PTGS1; PTGS2
MoA: Cyclooxygenase inhibitor
SMILES: CC(C)Cc1ccc(cc1)C(C)C(O)=O
InchiKey: HEFNNWSXXWATRW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
50976 BRD-A17655518 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90758 BRD-A17655518 HPTEC 1000 uM 24 h 0.0 0.0 0.0 -0.38 -1.28 1.45
91179 BRD-A17655518 HUH7 15 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
120291 BRD-A17655518 A549 10 uM 24 h -0.17 -0.72 0.0 0.0 0.0 0.0
120352 BRD-A17655518 HELA 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120415 BRD-A17655518 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120444 BRD-A17655518 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120491 BRD-A17655518 YAPC 0.37 uM 24 h -0.28 -1.16 0.46 -0.32 -1.06 0.74
128893 BRD-A17655518 A375 0.08 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.21
128909 BRD-A17655518 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128955 BRD-A17655518 HT29 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).