CMap Candidate Details

Structure:
CMap ID: C00444
Pert ID: BRD-A17664363
Compound Name: BRD-A17664363
Targets: NR5A1
MoA: Steroidogenic factor antagonist
SMILES: CCOC(=O)C(C)Oc1cccc2c1ccn(CC(=O)Nc1ccc(OC)cc1)c2=O
InchiKey: CFQXBSFRUQKYQA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
22046 BRD-A17664363 A375 10 uM 6 h -0.21 -0.87 0.02 0.26 0.93 0.26
22092 BRD-A17664363 A549 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.44
22371 BRD-A17664363 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22630 BRD-A17664363 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22910 BRD-A17664363 HEPG2 10 uM 6 h -0.35 -1.45 1.43 0.0 0.0 0.0
23216 BRD-A17664363 HT29 10 uM 6 h 0.0 0.0 0.0 0.2 0.7 0.02
23500 BRD-A17664363 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
23781 BRD-A17664363 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24074 BRD-A17664363 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
114951 BRD-A17664363 U2OS 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).