CMap Candidate Details

Structure:
CMap ID: C00045
Pert ID: BRD-A01787639
Compound Name: naftopidil
Targets: --
MoA: --
SMILES: COc1ccccc1N1CCN(CC(O)COc2cccc3ccccc23)CC1
InchiKey: HRRBJVNMSRJFHQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24369 BRD-A01787639 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25275 BRD-A01787639 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
52228 BRD-A01787639 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91011 BRD-A01787639 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
122893 BRD-A01787639 HEK293 0.04 uM 24 h 0.0 0.0 0.0 -0.21 -0.7 0.03
122939 BRD-A01787639 HELA 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122972 BRD-A01787639 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123018 BRD-A01787639 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123107 BRD-A01787639 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.79
123179 BRD-A01787639 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131242 BRD-A01787639 A549 0.03 uM 24 h -0.28 -1.15 0.44 -0.31 -1.05 0.71
131278 BRD-A01787639 HA1E 2.22 uM 24 h -0.28 -1.17 0.48 -0.34 -1.15 1.05
131355 BRD-A01787639 HUVEC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131395 BRD-A01787639 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 0.22 0.76 0.05
131434 BRD-A01787639 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131494 BRD-A01787639 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).