CMap Candidate Details

Structure:
CMap ID: C00451
Pert ID: BRD-A17819071
Compound Name: gedunin
Targets: HSP90AA1
MoA: HSP inhibitor
SMILES: CC1(C)C=CC(=O)[C@@]2(C)C1CC(=O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C5OC543)c6ccoc6
InchiKey: VOKBOMKQXKLQSI-UMZYLEKASA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5147 BRD-A17819071 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5255 BRD-A17819071 HA1E 10 uM 24 h 0.22 0.94 0.05 -0.4 -1.35 1.87
5502 BRD-A17819071 HCC515 10 uM 24 h 0.26 1.07 0.19 0.28 0.98 0.37
5827 BRD-A17819071 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5973 BRD-A17819071 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6065 BRD-A17819071 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6237 BRD-A17819071 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6317 BRD-A17819071 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).