CMap Candidate Details

Structure:
CMap ID: C04512
Pert ID: BRD-K06674495
Compound Name: nafamostat
Targets: --
MoA: --
SMILES: NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc2cc(ccc2c1)C(N)=N
InchiKey: MQQNFDZXWVTQEH-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122545 BRD-K06674495 A375 10 uM 24 h 0.26 1.1 0.24 0.0 0.0 0.0
122576 BRD-K06674495 A549 10 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.83
122718 BRD-K06674495 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122752 BRD-K06674495 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.22
122814 BRD-K06674495 YAPC 1.11 uM 24 h -0.25 -1.06 0.26 -0.27 -0.91 0.31
130913 BRD-K06674495 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130934 BRD-K06674495 HEK293 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130964 BRD-K06674495 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130997 BRD-K06674495 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131040 BRD-K06674495 HUVEC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131117 BRD-K06674495 MDAMB231 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131150 BRD-K06674495 PC3 0.03 uM 24 h 0.0 0.0 0.0 0.24 0.83 0.12
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).