CMap Candidate Details

Structure:
CMap ID: C04518
Pert ID: BRD-K06712146
Compound Name: YM-90709
Targets: IL5RA
MoA: IL5 inhibitor
SMILES: COc1cc2CC(C)(C)n3c(cc4nc5ccccc5nc34)-c2cc1OC
InchiKey: HIXSPVQXXDULHS-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5296 BRD-K06712146 HA1E 10 uM 24 h 0.27 1.12 0.27 0.24 0.86 0.16
5572 BRD-K06712146 HCC515 10 uM 24 h -0.26 -1.1 0.35 -0.21 -0.72 0.04
5878 BRD-K06712146 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.08 0.81
6002 BRD-K06712146 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6259 BRD-K06712146 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6401 BRD-K06712146 VCAP 10 uM 24 h 0.2 0.86 0.01 -0.35 -1.17 1.14
44288 BRD-K06712146 A375 10 uM 6 h -0.21 -0.86 0.01 0.0 0.0 0.0
44663 BRD-K06712146 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44833 BRD-K06712146 ASC 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.35
45766 BRD-K06712146 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.01 0.57
45948 BRD-K06712146 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46267 BRD-K06712146 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).