CMap Candidate Details

Structure:
CMap ID: C04536
Pert ID: BRD-K06749501
Compound Name: GSK-1838705A
Targets: --
MoA: --
SMILES: CNC(=O)c1c(F)cccc1Nc1nc(Nc2cc3N(CCc3cc2OC)C(=O)CN(C)C)nc2[nH]ccc12
InchiKey: HZTYDQRUAWIZRE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
496 BRD-K06749501 BJAB 10 uM 24 h 0.24 0.98 0.09 -0.34 -1.16 1.1
535 BRD-K06749501 HBL1 10 uM 24 h 0.23 0.98 0.09 -0.25 -0.84 0.17
599 BRD-K06749501 K562 10 uM 4 h 0.0 0.0 0.0 0.0 0.0 0.0
634 BRD-K06749501 KMS34 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
680 BRD-K06749501 MINO 10 uM 24 h 0.32 1.32 0.78 0.0 0.0 0.0
727 BRD-K06749501 NALM6 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
762 BRD-K06749501 OCILY19 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
832 BRD-K06749501 OCILY3 0.125 uM 4 h -0.26 -1.09 0.33 -0.31 -1.03 0.64
869 BRD-K06749501 SKMEL5 0.04 uM 24 h -0.22 -0.94 0.07 0.0 0.0 0.0
911 BRD-K06749501 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
939 BRD-K06749501 TMD8 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.22
90863 BRD-K06749501 MCF10A 1.11 uM 24 h -0.18 -0.76 0.0 0.0 0.0 0.0
97333 BRD-K06749501 HAP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97354 BRD-K06749501 A375 0.66 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).