CMap Candidate Details

Structure:
CMap ID: C04537
Pert ID: BRD-K06750613
Compound Name: GSK-1059615
Targets: --
MoA: --
SMILES: O=C1NC(=O)C(S1)=Cc1ccc2nccc(-c3ccncc3)c2c1
InchiKey: QDITZBLZQQZVEE-YBEGLDIGSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49803 BRD-K06750613 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50144 BRD-K06750613 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50332 BRD-K06750613 HCC515 10 uM 6 h 0.0 0.0 0.0 0.26 0.91 0.24
51123 BRD-K06750613 VCAP 10 uM 6 h 0.18 0.73 0.0 -0.18 -0.6 0.0
96060 BRD-K06750613 PHH 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.32 1.71
97325 BRD-K06750613 HAP1 0.66 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.35
117689 BRD-K06750613 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117834 BRD-K06750613 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117884 BRD-K06750613 HT29 10 uM 24 h 0.0 0.0 0.0 0.21 0.76 0.05
117932 BRD-K06750613 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117980 BRD-K06750613 PC3 0.37 uM 24 h 0.26 1.09 0.23 -0.33 -1.12 0.93
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).