CMap Candidate Details

Structure:
CMap ID: C04540
Pert ID: BRD-K06762493
Compound Name: isbufylline
Targets: --
MoA: --
SMILES: CC(C)Cn1cnc2n(C)c(=O)n(C)c(=O)c12
InchiKey: WHUWQSQEVISUMC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96807 BRD-K06762493 PC3 3.33 uM 24 h 0.24 1.0 0.1 0.0 0.0 0.0
122546 BRD-K06762493 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122600 BRD-K06762493 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122633 BRD-K06762493 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122719 BRD-K06762493 MCF10A 1.11 uM 24 h 0.18 0.73 0.0 0.0 0.0 0.0
122772 BRD-K06762493 MDAMB231 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.93
130884 BRD-K06762493 A549 2.22 uM 24 h -0.22 -0.9 0.04 -0.29 -0.97 0.45
130965 BRD-K06762493 HELA 0.01 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.81
130998 BRD-K06762493 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.4 1.4 2.18
131041 BRD-K06762493 HUVEC 0.08 uM 24 h 0.29 1.23 0.49 0.0 0.0 0.0
131082 BRD-K06762493 MCF??7.00 0.03 uM 24 h 0.34 1.41 1.03 0.0 0.0 0.0
131183 BRD-K06762493 YAPC 2.22 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.28
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).