CMap Candidate Details

Structure:
CMap ID: C00455
Pert ID: BRD-A17883755
Compound Name: lenalidomide
Targets: CRBN; TNF
MoA: Anti-cancer agent
SMILES: Nc1cccc2C(=O)N(Cc12)C1CCC(=O)NC1=O
InchiKey: GOTYRUGSSMKFNF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
54 BRD-A17883755 BJAB 10 uM 4 h 0.37 1.55 1.48 0.0 0.0 0.0
88 BRD-A17883755 HBL1 2.5 uM 24 h 0.0 0.0 0.0 -0.4 -1.34 1.85
151 BRD-A17883755 K562 10 uM 4 h 0.23 0.96 0.08 0.27 0.95 0.32
176 BRD-A17883755 KMS34 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
218 BRD-A17883755 NALM6 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
257 BRD-A17883755 OCILY10 10 uM 24 h 0.19 0.8 0.0 0.3 1.06 0.59
285 BRD-A17883755 OCILY19 2.5 uM 24 h -0.23 -0.96 0.09 0.0 0.0 0.0
332 BRD-A17883755 OCILY3 2.5 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
375 BRD-A17883755 SKMEL5 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
406 BRD-A17883755 THP1 10 uM 24 h 0.0 0.0 0.0 0.32 1.15 0.88
462 BRD-A17883755 TMD8 10 uM 4 h 0.0 0.0 0.0 0.0 0.0 0.0
8862 BRD-A17883755 A375 200 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9069 BRD-A17883755 A549 200 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9273 BRD-A17883755 AGS 200 uM 6 h 0.25 1.05 0.17 0.26 0.93 0.28
9576 BRD-A17883755 H1299 200 uM 6 h 0.27 1.14 0.31 0.0 0.0 0.0
10298 BRD-A17883755 HCC515 200 uM 6 h 0.0 0.0 0.0 -0.26 -0.87 0.23
10385 BRD-A17883755 HCT116 200 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10655 BRD-A17883755 HEPG2 200 uM 6 h 0.0 0.0 0.0 -0.31 -1.05 0.72
11325 BRD-A17883755 NCIH2073 200 uM 6 h -0.31 -1.29 0.79 -0.34 -1.15 1.05
11644 BRD-A17883755 NCIH508 200 uM 6 h -0.21 -0.87 0.02 -0.32 -1.07 0.76
11895 BRD-A17883755 NCIH596 200 uM 6 h 0.0 0.0 0.0 -0.3 -1.0 0.55
12652 BRD-A17883755 SW480 200 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13133 BRD-A17883755 U937 200 uM 6 h 0.0 0.0 0.0 0.32 1.12 0.77
13418 BRD-A17883755 VCAP 200 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95845 BRD-A17883755 NPC 1.11 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
120419 BRD-A17883755 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120446 BRD-A17883755 PC3 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120497 BRD-A17883755 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128912 BRD-A17883755 HA1E 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128931 BRD-A17883755 HELA 0.74 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
128958 BRD-A17883755 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).