CMap Candidate Details

Structure:
CMap ID: C04567
Pert ID: BRD-K06854232
Compound Name: AM-580
Targets: RARA
MoA: Retinoid receptor agonist
SMILES: CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)Nc1ccc(cc1)C(O)=O
InchiKey: SZWKGOZKRMMLAJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1196 BRD-K06854232 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4349 BRD-K06854232 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.65
4883 BRD-K06854232 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9349 BRD-K06854232 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9655 BRD-K06854232 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9932 BRD-K06854232 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.94
10720 BRD-K06854232 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.31 1.08 0.66
10936 BRD-K06854232 HT29 10 uM 24 h -0.33 -1.39 1.09 -0.39 -1.3 1.65
11188 BRD-K06854232 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11406 BRD-K06854232 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12256 BRD-K06854232 NOMO1 10 uM 6 h -0.28 -1.16 0.45 0.0 0.0 0.0
12721 BRD-K06854232 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13026 BRD-K06854232 THP1 10 uM 6 h 0.0 0.0 0.0 0.29 1.04 0.56
13200 BRD-K06854232 U937 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.76 0.07
44836 BRD-K06854232 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46270 BRD-K06854232 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46585 BRD-K06854232 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90529 BRD-K06854232 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96333 BRD-K06854232 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97693 BRD-K06854232 NKDBA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98742 BRD-K06854232 NPC 10 uM 24 h -0.17 -0.73 0.0 0.0 0.0 0.0
98864 BRD-K06854232 NEU 10 uM 24 h 0.18 0.75 0.0 0.0 0.0 0.0
100016 BRD-K06854232 U2OS 10 uM 6 h 0.24 0.98 0.09 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).