CMap Candidate Details

Structure:
CMap ID: C04568
Pert ID: BRD-K06858286
Compound Name: cabazitaxel
Targets: --
MoA: --
SMILES: CO[C@@H]1C[C@H]2OC[C@@]2(OC(C)=O)[C@H]2[C@@H](OC(=O)c3ccccc3)[C@@]3(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)c4ccccc4)C(C)=C([C@@H](OC)C(=O)[C@]12C)C3(C)C
InchiKey: BMQGVNUXMIRLCK-VCPXPHFHSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122578 BRD-K06858286 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122722 BRD-K06858286 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122794 BRD-K06858286 PC3 1.11 uM 24 h -0.28 -1.18 0.5 -0.31 -1.05 0.71
130868 BRD-K06858286 A375 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130915 BRD-K06858286 HA1E 2.22 uM 24 h -0.23 -0.94 0.08 -0.43 -1.45 15.35
130936 BRD-K06858286 HEK293 0.08 uM 24 h -0.24 -1.01 0.17 -0.42 -1.41 2.02
130968 BRD-K06858286 HELA 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131001 BRD-K06858286 HT29 0.01 uM 24 h -0.28 -1.15 0.44 0.0 0.0 0.0
131044 BRD-K06858286 HUVEC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131083 BRD-K06858286 MCF??7.00 0.01 uM 24 h 0.26 1.09 0.24 -0.26 -0.88 0.26
131119 BRD-K06858286 MDAMB231 0.08 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
131185 BRD-K06858286 YAPC 0.03 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.35
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).