CMap Candidate Details

Structure:
CMap ID: C04574
Pert ID: BRD-K06878038
Compound Name: deferiprone
Targets: UGT1A6
MoA: Chelating agent
SMILES: Cc1c(O)c(=O)ccn1C
InchiKey: TZXKOCQBRNJULO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25323 BRD-K06878038 VCAP 10 uM 24 h 0.0 0.0 0.0 0.37 1.3 1.56
122547 BRD-K06878038 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122635 BRD-K06878038 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122659 BRD-K06878038 HELA 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122680 BRD-K06878038 HT29 0.125 uM 24 h -0.25 -1.02 0.19 0.0 0.0 0.0
122723 BRD-K06878038 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122755 BRD-K06878038 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.05
122816 BRD-K06878038 YAPC 0.04 uM 24 h 0.22 0.9 0.02 0.0 0.0 0.0
130885 BRD-K06878038 A549 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130916 BRD-K06878038 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131045 BRD-K06878038 HUVEC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131120 BRD-K06878038 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 0.32 1.15 0.87
131151 BRD-K06878038 PC3 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).