CMap Candidate Details

Structure:
CMap ID: C04578
Pert ID: BRD-K06890060
Compound Name: alda-1
Targets: ALDH2
MoA: Aldehyde dehydrogenase activator
SMILES: Clc1cccc(Cl)c1C(=O)NCc2ccc3OCOc3c2
InchiKey: NMKJFZCBCIUYHI-UHFFFAOYSA-N
Compound Aliases: ALDA-1

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8903 BRD-K06890060 A375 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9084 BRD-K06890060 A549 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9656 BRD-K06890060 H1299 40 uM 6 h 0.0 0.0 0.0 -0.3 -1.0 0.55
10028 BRD-K06890060 HA1E 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10300 BRD-K06890060 HCC515 40 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.58
10452 BRD-K06890060 HCT116 40 uM 6 h 0.0 0.0 0.0 0.24 0.85 0.14
10721 BRD-K06890060 HEPG2 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10937 BRD-K06890060 HT29 40 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.86
11179 BRD-K06890060 MCF??7.00 40 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.7
11407 BRD-K06890060 NCIH2073 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11704 BRD-K06890060 NCIH508 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11976 BRD-K06890060 NCIH596 40 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.18
12257 BRD-K06890060 NOMO1 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12495 BRD-K06890060 PC3 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12722 BRD-K06890060 SW480 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13201 BRD-K06890060 U937 40 uM 6 h 0.0 0.0 0.0 -0.23 -0.78 0.09
13574 BRD-K06890060 VCAP 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).