CMap Candidate Details

Structure:
CMap ID: C00458
Pert ID: BRD-A18202423
Compound Name: CPCCOEt
Targets: GRM1
MoA: Glutamate receptor antagonist
SMILES: CCOC(=O)C12CC2C(=NO)c3ccccc3O1
InchiKey: FXCTZFMSAHZQTR-UHFFFAOYSA-N
Compound Aliases: cpccoet

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4006 BRD-A18202423 HA1E 10 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.72
4281 BRD-A18202423 HCC515 10 uM 24 h -0.19 -0.81 0.0 -0.24 -0.82 0.15
4736 BRD-A18202423 PC3 10 uM 6 h -0.19 -0.81 0.0 -0.26 -0.88 0.24
4839 BRD-A18202423 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.67
37047 BRD-A18202423 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37328 BRD-A18202423 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37451 BRD-A18202423 ASC 10 uM 24 h 0.0 0.0 0.0 -0.45 -1.52 15.35
37987 BRD-A18202423 HT29 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.78 0.09
38132 BRD-A18202423 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38302 BRD-A18202423 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38606 BRD-A18202423 PHH 10 uM 24 h 0.21 0.89 0.02 0.0 0.0 0.0
38825 BRD-A18202423 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).