CMap Candidate Details

Structure:
CMap ID: C04581
Pert ID: BRD-K06895174
Compound Name: cisapride
Targets: HTR4; KCNH2
MoA: Serotonin receptor agonist
SMILES: CO[C@H]1CN(CCCOc2ccc(F)cc2)CC[C@H]1NC(=O)c1cc(Cl)c(N)cc1OC
InchiKey: DCSUBABJRXZOMT-IRLDBZIGSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5179 BRD-K06895174 A375 10 uM 6 h 0.0 0.0 0.0 0.29 1.04 0.56
5426 BRD-K06895174 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5755 BRD-K06895174 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5879 BRD-K06895174 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6516 BRD-K06895174 VCAP 10 uM 6 h -0.22 -0.91 0.06 0.28 0.98 0.37
24552 BRD-K06895174 A549 10 uM 24 h 0.21 0.89 0.02 -0.2 -0.69 0.02
25082 BRD-K06895174 MCF??7.00 10 uM 6 h 0.22 0.93 0.05 -0.26 -0.89 0.26
25231 BRD-K06895174 PC3 10 uM 6 h 0.21 0.86 0.01 0.0 0.0 0.0
44837 BRD-K06895174 ASC 10 uM 24 h 0.0 0.0 0.0 0.22 0.8 0.08
45414 BRD-K06895174 HT29 10 uM 6 h -0.24 -0.99 0.14 0.0 0.0 0.0
45951 BRD-K06895174 NPC 10 uM 24 h -0.28 -1.18 0.5 -0.39 -1.3 1.6
46271 BRD-K06895174 PHH 10 uM 24 h 0.29 1.19 0.42 0.0 0.0 0.0
46586 BRD-K06895174 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).