CMap Candidate Details

Structure:
CMap ID: C04595
Pert ID: BRD-K06926592
Compound Name: tretinoin
Targets: RARA; RARB; RARG; RORB
MoA: Retinoid receptor ligand; Retinoid receptor agonist
SMILES: CC(=CC=CC(=CC(=O)O)C)C=CC1=C(C)CCCC1(C)C
InchiKey: SHGAZHPCJJPHSC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2832 BRD-K06926592 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3138 BRD-K06926592 HCC515 10 uM 24 h 0.18 0.73 0.0 0.25 0.89 0.2
3720 BRD-K06926592 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.75 0.06
39425 BRD-K06926592 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39624 BRD-K06926592 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40225 BRD-K06926592 HT29 10 uM 6 h 0.0 0.0 0.0 0.28 0.99 0.39
40588 BRD-K06926592 MCF??7.00 10 uM 6 h -0.2 -0.82 0.0 0.0 0.0 0.0
40748 BRD-K06926592 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41048 BRD-K06926592 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41376 BRD-K06926592 SKB 10 uM 24 h 0.0 0.0 0.0 0.36 1.28 1.37
51421 BRD-K06926592 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52855 BRD-K06926592 HEPG2 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53140 BRD-K06926592 MCF10A 12 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
96485 BRD-K06926592 A375 1.11 uM 24 h 0.2 0.85 0.01 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).