CMap Candidate Details

Structure:
CMap ID: C04601
Pert ID: BRD-K06956503
Compound Name: BRD-K06956503
Targets: GBA
MoA: Glucosylceramidase inhibitor
SMILES: Clc1ccc(CN(CCCCNC(=S)NCCCc2c[nH]cn2)c2ccc(Br)cn2)cc1
InchiKey: ISTWZTLJICEOOO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
13751 BRD-K06956503 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
14081 BRD-K06956503 A549 10 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.62
14405 BRD-K06956503 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
14747 BRD-K06956503 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.08 0.78
14976 BRD-K06956503 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
15288 BRD-K06956503 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
15731 BRD-K06956503 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
15897 BRD-K06956503 VCAP 10 uM 24 h -0.18 -0.77 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).