CMap Candidate Details

Structure:
CMap ID: C00465
Pert ID: BRD-A18497530
Compound Name: 5-iodotubercidin
Targets: MAPK3
MoA: Adenosine kinase inhibitor
SMILES: Nc1ncnc2n(cc(I)c12)C3OC(CO)C(O)C3O
InchiKey: WHSIXKUPQCKWBY-UHFFFAOYSA-N
Compound Aliases: 5-IODOTUBERCIDIN

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33977 BRD-A18497530 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35672 BRD-A18497530 NPC 10 uM 24 h -0.31 -1.31 0.82 0.0 0.0 0.0
36431 BRD-A18497530 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96194 BRD-A18497530 A549 0.37 uM 24 h 0.0 0.0 0.0 -0.19 -0.64 0.01
96264 BRD-A18497530 U2OS 1.11 uM 24 h 0.25 1.05 0.16 0.0 0.0 0.0
118678 BRD-A18497530 A375 0.37 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
118746 BRD-A18497530 HA1E 1.11 uM 24 h -0.25 -1.03 0.19 0.0 0.0 0.0
118785 BRD-A18497530 HCC515 1.11 uM 24 h -0.23 -0.96 0.1 0.0 0.0 0.0
118826 BRD-A18497530 HEPG2 1.11 uM 24 h -0.18 -0.74 0.0 -0.29 -0.99 0.5
118869 BRD-A18497530 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.23 0.8 0.08
118912 BRD-A18497530 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.2 0.71 0.02
118945 BRD-A18497530 PC3 0.37 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).