CMap Candidate Details

Structure:
CMap ID: C04669
Pert ID: BRD-K07237224
Compound Name: moclobemide
Targets: MAOA
MoA: Monoamine oxidase inhibitor
SMILES: Clc1ccc(cc1)C(=O)NCCN1CCOCC1
InchiKey: YHXISWVBGDMDLQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25324 BRD-K07237224 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122553 BRD-K07237224 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122639 BRD-K07237224 HEK293 10 uM 24 h 0.23 0.94 0.06 -0.31 -1.04 0.68
122662 BRD-K07237224 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122685 BRD-K07237224 HT29 3.33 uM 24 h 0.23 0.94 0.06 0.0 0.0 0.0
122731 BRD-K07237224 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.71 0.03
122758 BRD-K07237224 MCF??7.00 1.11 uM 24 h 0.18 0.74 0.0 -0.32 -1.08 0.78
122819 BRD-K07237224 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130889 BRD-K07237224 A549 0.25 uM 24 h -0.21 -0.86 0.02 0.22 0.78 0.07
130920 BRD-K07237224 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131053 BRD-K07237224 HUVEC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131126 BRD-K07237224 MDAMB231 0.03 uM 24 h 0.29 1.23 0.49 0.34 1.21 1.14
131155 BRD-K07237224 PC3 2.22 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.69
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).