CMap Candidate Details

Structure:
CMap ID: C00467
Pert ID: BRD-A18579359
Compound Name: wiskostatin
Targets: WASL
MoA: Neural Wiskott-Aldrich syndrome protein inhibitor
SMILES: CN(C)CC(O)Cn1c2ccc(Br)cc2c3cc(Br)ccc13
InchiKey: XUBJEDZHBUPBKL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2797 BRD-A18579359 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3310 BRD-A18579359 HCC515 10 uM 6 h 0.0 0.0 0.0 0.44 1.56 2.33
3429 BRD-A18579359 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3668 BRD-A18579359 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39034 BRD-A18579359 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39264 BRD-A18579359 A549 10 uM 24 h 0.24 0.98 0.09 0.0 0.0 0.0
39551 BRD-A18579359 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39880 BRD-A18579359 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40167 BRD-A18579359 HT29 10 uM 6 h 0.3 1.26 0.57 0.0 0.0 0.0
40421 BRD-A18579359 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.25
40977 BRD-A18579359 NPC 10 uM 24 h 0.21 0.89 0.02 0.27 0.96 0.33
41300 BRD-A18579359 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).