CMap Candidate Details

Structure:
CMap ID: C00470
Pert ID: BRD-A18620900
Compound Name: estriol
Targets: ESR1; ESR2
MoA: Estrogen receptor agonist
SMILES: C[C@]12CCC3C(CCc4cc(O)ccc34)C1C[C@@H](O)[C@@H]2O
InchiKey: PROQIPRRNZUXQM-YDGSGPMOSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6622 BRD-A18620900 A375 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
7211 BRD-A18620900 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8556 BRD-A18620900 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120300 BRD-A18620900 A549 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120369 BRD-A18620900 HELA 10 uM 3 h 0.0 0.0 0.0 -0.26 -0.88 0.25
120426 BRD-A18620900 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120505 BRD-A18620900 YAPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128965 BRD-A18620900 HT29 0.01 uM 24 h 0.2 0.82 0.0 0.4 1.4 2.18
128983 BRD-A18620900 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).