CMap Candidate Details

Structure:
CMap ID: C04820
Pert ID: BRD-K07609981
Compound Name: dexloxiglumide
Targets: CCKAR
MoA: CCK receptor antagonist
SMILES: CCCCCN(CCCOC)C(=O)[C@@H](CCC(O)=O)NC(=O)c1ccc(Cl)c(Cl)c1
InchiKey: QNQZBKQEIFTHFZ-GOSISDBHSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122558 BRD-K07609981 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122610 BRD-K07609981 HA1E 10 uM 24 h 0.0 0.0 0.0 0.25 0.87 0.17
122646 BRD-K07609981 HEK293 1.11 uM 24 h 0.33 1.37 0.97 0.25 0.88 0.18
122741 BRD-K07609981 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122779 BRD-K07609981 MDAMB231 1.11 uM 24 h 0.24 1.01 0.11 0.3 1.05 0.57
122803 BRD-K07609981 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122824 BRD-K07609981 YAPC 10 uM 24 h -0.21 -0.86 0.02 -0.23 -0.79 0.1
130892 BRD-K07609981 A549 0.25 uM 24 h 0.28 1.16 0.34 0.0 0.0 0.0
130981 BRD-K07609981 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131009 BRD-K07609981 HT29 0.25 uM 24 h 0.0 0.0 0.0 0.38 1.34 1.72
131063 BRD-K07609981 HUVEC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131096 BRD-K07609981 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).