CMap Candidate Details

Structure:
CMap ID: C00489
Pert ID: BRD-A19248578
Compound Name: latrunculin-b
Targets: --
MoA: --
SMILES: C[C@H]1CC[C@@H]2C[C@H](C[C@@](O)(O2)C2CSC(=O)N2)OC(=O)C=C(C)/CCC=C/1
InchiKey: NSHPHXHGRHSMIK-IWZLBRJHSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25687 BRD-A19248578 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25873 BRD-A19248578 A549 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.15 1.08
26194 BRD-A19248578 ASC 10 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.72
26539 BRD-A19248578 HA1E 10 uM 6 h -0.21 -0.87 0.02 0.0 0.0 0.0
26854 BRD-A19248578 HCC515 10 uM 6 h 0.0 0.0 0.0 0.34 1.2 1.07
27157 BRD-A19248578 HT29 10 uM 6 h 0.0 0.0 0.0 0.26 0.93 0.26
27649 BRD-A19248578 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.69 0.02
27788 BRD-A19248578 NEU 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.23 1.25
28097 BRD-A19248578 NPC 10 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.25
28561 BRD-A19248578 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
28735 BRD-A19248578 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
29046 BRD-A19248578 SKB 10 uM 24 h 0.0 0.0 0.0 0.27 0.96 0.34
29584 BRD-A19248578 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
90881 BRD-A19248578 MCF10A 4 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).