CMap Candidate Details

Structure:
CMap ID: C00490
Pert ID: BRD-A19374631
Compound Name: vinpocetine
Targets: PDE1A
MoA: Sodium channel blocker; Phosphodiesterase inhibitor
SMILES: CCOC(=O)C1=CC2(CC)CCCN3CCc4c(C32)n1c5ccccc45
InchiKey: DDNCQMVWWZOMLN-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1683 BRD-A19374631 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.2 1.19
1813 BRD-A19374631 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2321 BRD-A19374631 PC3 10 uM 6 h 0.0 0.0 0.0 0.28 1.01 0.44
2680 BRD-A19374631 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42000 BRD-A19374631 A549 10 uM 6 h -0.22 -0.93 0.07 0.0 0.0 0.0
42182 BRD-A19374631 ASC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.61
42527 BRD-A19374631 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42835 BRD-A19374631 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43254 BRD-A19374631 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43382 BRD-A19374631 NPC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
43699 BRD-A19374631 PHH 10 uM 24 h -0.24 -0.98 0.12 -0.24 -0.79 0.11
43996 BRD-A19374631 SKB 10 uM 24 h 0.29 1.21 0.44 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).