CMap Candidate Details

Structure:
CMap ID: C00494
Pert ID: BRD-A19633847
Compound Name: perhexiline
Targets: CPT1A; CPT2
MoA: Carnitine palmitoyltransferase inhibitor
SMILES: C(C(C1CCCCC1)C1CCCCC1)C1CCCCN1
InchiKey: CYXKNKQEMFBLER-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8864 BRD-A19633847 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9580 BRD-A19633847 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10003 BRD-A19633847 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10321 BRD-A19633847 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10657 BRD-A19633847 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.34 1.19 1.02
11328 BRD-A19633847 NCIH2073 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.75 0.06
11898 BRD-A19633847 NCIH596 10 uM 6 h -0.2 -0.81 0.0 -0.46 -1.54 15.35
12656 BRD-A19633847 SW480 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.9 0.28
13047 BRD-A19633847 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13134 BRD-A19633847 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13526 BRD-A19633847 VCAP 10 uM 6 h 0.26 1.07 0.2 0.43 1.53 2.29
90525 BRD-A19633847 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120937 BRD-A19633847 HEK293 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.86
120996 BRD-A19633847 HELA 10 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
121010 BRD-A19633847 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121030 BRD-A19633847 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121068 BRD-A19633847 PC3 10 uM 24 h 0.0 0.0 0.0 -0.46 -1.54 15.35
121095 BRD-A19633847 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).