CMap Candidate Details

Structure:
CMap ID: C00496
Pert ID: BRD-A19736161
Compound Name: ondansetron
Targets: HTR3A
MoA: Serotonin receptor antagonist
SMILES: Cc1nccn1CC1CCc2c(C1=O)c1ccccc1n2C
InchiKey: FELGMEQIXOGIFQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6623 BRD-A19736161 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7059 BRD-A19736161 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7381 BRD-A19736161 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7514 BRD-A19736161 HCC515 10 uM 6 h -0.25 -1.05 0.24 0.0 0.0 0.0
20186 BRD-A19736161 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.19
20830 BRD-A19736161 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
21675 BRD-A19736161 VCAP 10 uM 6 h 0.26 1.1 0.24 0.0 0.0 0.0
91338 BRD-A19736161 HUH7 12 uM 72 h 0.25 1.06 0.19 0.32 1.15 0.89
120934 BRD-A19736161 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120983 BRD-A19736161 HELA 1.11 uM 24 h 0.17 0.69 0.0 0.0 0.0 0.0
121092 BRD-A19736161 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.33 1.18 0.98
129182 BRD-A19736161 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129214 BRD-A19736161 PC3 0.74 uM 24 h 0.17 0.7 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).