CMap Candidate Details

Structure:
CMap ID: C05018
Pert ID: BRD-K08252256
Compound Name: diclofenac
Targets: PTGS1; PTGS2
MoA: Cyclooxygenase inhibitor
SMILES: OC(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl
InchiKey: DCOPUUMXTXDBNB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5575 BRD-K08252256 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6519 BRD-K08252256 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42052 BRD-K08252256 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42282 BRD-K08252256 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42616 BRD-K08252256 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42919 BRD-K08252256 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43780 BRD-K08252256 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44061 BRD-K08252256 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91239 BRD-K08252256 HUH7 12 uM 72 h 0.22 0.92 0.04 -0.25 -0.86 0.21
98866 BRD-K08252256 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99217 BRD-K08252256 NPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
100031 BRD-K08252256 U2OS 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.92 0.34
121214 BRD-K08252256 HA1E 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121304 BRD-K08252256 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129242 BRD-K08252256 A375 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129270 BRD-K08252256 HELA 0.25 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
129325 BRD-K08252256 MCF??7.00 0.01 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
129362 BRD-K08252256 YAPC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).