CMap Candidate Details

Structure:
CMap ID: C00503
Pert ID: BRD-A19952358
Compound Name: closantel
Targets: --
MoA: --
SMILES: Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O
InchiKey: JMPFSEBWVLAJKM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91197 BRD-A19952358 HUH7 4 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
121364 BRD-A19952358 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121384 BRD-A19952358 HA1E 1.11 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
121404 BRD-A19952358 HELA 1.11 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.79
121507 BRD-A19952358 YAPC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129488 BRD-A19952358 HT29 0.08 uM 24 h 0.31 1.29 0.66 -0.22 -0.75 0.06
129518 BRD-A19952358 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129551 BRD-A19952358 PC3 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).