CMap Candidate Details

Structure:
CMap ID: C00507
Pert ID: BRD-A20119038
Compound Name: mecamylamine
Targets: CHRNA2
MoA: Acetylcholine receptor antagonist
SMILES: CNC1(C)C2CCC(C2)C1(C)C
InchiKey: IMYZQPCYWPFTAG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120884 BRD-A20119038 A549 0.37 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.56
120903 BRD-A20119038 HA1E 0.125 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
120939 BRD-A20119038 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120985 BRD-A20119038 HELA 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121031 BRD-A20119038 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
121070 BRD-A20119038 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121097 BRD-A20119038 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129093 BRD-A20119038 A375 2.22 uM 24 h 0.0 0.0 0.0 0.36 1.29 1.49
129183 BRD-A20119038 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).