CMap Candidate Details

Structure:
CMap ID: C05074
Pert ID: BRD-K08438429
Compound Name: BRD-K08438429
Targets: GBA; SSTR4
MoA: Somatostatin receptor agonist
SMILES: Clc1ccc(CN(CCCNC(=S)NCCCc2c[nH]cn2)c3ccc(Br)cn3)cc1Cl
InchiKey: UREJDUPKGMFJRU-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4048 BRD-K08438429 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4541 BRD-K08438429 HCC515 10 uM 6 h 0.0 0.0 0.0 0.31 1.09 0.67
4770 BRD-K08438429 PC3 10 uM 6 h 0.21 0.88 0.01 0.0 0.0 0.0
4886 BRD-K08438429 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44292 BRD-K08438429 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44515 BRD-K08438429 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44841 BRD-K08438429 ASC 10 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.63
45149 BRD-K08438429 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45416 BRD-K08438429 HT29 10 uM 6 h 0.19 0.77 0.0 0.3 1.07 0.63
45645 BRD-K08438429 MCF??7.00 10 uM 24 h -0.27 -1.12 0.38 0.26 0.92 0.26
45955 BRD-K08438429 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46275 BRD-K08438429 PHH 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.72 0.04
46590 BRD-K08438429 SKB 10 uM 24 h 0.0 0.0 0.0 0.33 1.15 0.9
100034 BRD-K08438429 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).