CMap Candidate Details

Structure:
CMap ID: C05097
Pert ID: BRD-K08502430
Compound Name: angiogenesis-inhibitor
Targets: EGFR
MoA: Angiogenesis inhibitor
SMILES: O=C/1Nc2ccccc2C1=C/c3c[nH]cn3
InchiKey: VEEGZPWAAPPXRB-BJMVGYQFSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1539 BRD-K08502430 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1878 BRD-K08502430 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2304 BRD-K08502430 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41717 BRD-K08502430 A375 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.86 0.22
42054 BRD-K08502430 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42284 BRD-K08502430 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42618 BRD-K08502430 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42921 BRD-K08502430 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43156 BRD-K08502430 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.57
43477 BRD-K08502430 NPC 10 uM 24 h 0.27 1.13 0.28 0.23 0.82 0.09
43782 BRD-K08502430 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44062 BRD-K08502430 SKB 10 uM 24 h 0.24 0.98 0.09 0.0 0.0 0.0
90292 BRD-K08502430 VCAP 10 uM 24 h -0.26 -1.1 0.34 -0.26 -0.88 0.25
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).