CMap Candidate Details

Structure:
CMap ID: C05119
Pert ID: BRD-K08586861
Compound Name: ramatroban
Targets: PTGDR2; TBXA2R
MoA: Prostanoid receptor antagonist
SMILES: OC(=O)CCn1c2CC[C@H](Cc2c2ccccc12)NS(=O)(=O)c1ccc(F)cc1
InchiKey: LDXDSHIEDAPSSA-OAHLLOKOSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121144 BRD-K08586861 A375 1.11 uM 24 h 0.23 0.95 0.06 0.28 1.01 0.44
121181 BRD-K08586861 A549 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121217 BRD-K08586861 HA1E 0.37 uM 24 h 0.29 1.23 0.49 0.0 0.0 0.0
121287 BRD-K08586861 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121307 BRD-K08586861 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129260 BRD-K08586861 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129291 BRD-K08586861 HT29 0.25 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.4
129365 BRD-K08586861 YAPC 0.03 uM 24 h -0.24 -1.01 0.16 -0.29 -0.97 0.45
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).