CMap Candidate Details

Structure:
CMap ID: C00513
Pert ID: BRD-A20239487
Compound Name: BRD-A20239487
Targets: --
MoA: --
SMILES: CC(C)NCC(O)COc1ccc(CC(N)=O)cc1
InchiKey: METKIMKYRPQLGS-UHFFFAOYSA-N
Compound Aliases: atenolol-(+/-)

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
50285 BRD-A20239487 HCC515 10 uM 6 h 0.0 0.0 0.0 0.31 1.11 0.72
51092 BRD-A20239487 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.73 0.05
90780 BRD-A20239487 HPTEC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
127008 BRD-A20239487 A375 10 uM 24 h -0.23 -0.97 0.11 0.28 0.98 0.38
127062 BRD-A20239487 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127127 BRD-A20239487 HT29 0.37 uM 24 h -0.23 -0.96 0.1 0.35 1.25 1.29
127176 BRD-A20239487 MCF10A 0.04 uM 24 h 0.24 1.02 0.13 0.0 0.0 0.0
127198 BRD-A20239487 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127225 BRD-A20239487 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127266 BRD-A20239487 THP1 10 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.42
135028 BRD-A20239487 A549 0.03 uM 24 h -0.35 -1.45 1.43 0.33 1.16 0.9
135072 BRD-A20239487 HA1E 0.03 uM 24 h 0.2 0.85 0.01 0.0 0.0 0.0
135124 BRD-A20239487 HELA 2.22 uM 24 h -0.3 -1.27 0.74 0.2 0.7 0.01
135160 BRD-A20239487 JURKAT 0.25 uM 24 h 0.37 1.53 1.45 0.0 0.0 0.0
135245 BRD-A20239487 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135317 BRD-A20239487 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).