CMap Candidate Details

Structure:
CMap ID: C05135
Pert ID: BRD-K08640512
Compound Name: RS-100329
Targets: ADRA1A
MoA: Adrenergic receptor antagonist
SMILES: Cc1c[nH]c(=O)n(CCCN2CCN(CC2)c2ccccc2OCC(F)(F)F)c1=O
InchiKey: RCOBWVAGWYRNHZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4191 BRD-K08640512 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4352 BRD-K08640512 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4772 BRD-K08640512 PC3 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.89 0.27
5029 BRD-K08640512 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.77 0.08
44296 BRD-K08640512 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44667 BRD-K08640512 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44844 BRD-K08640512 ASC 10 uM 24 h 0.24 0.99 0.09 0.32 1.15 0.88
45153 BRD-K08640512 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45420 BRD-K08640512 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45769 BRD-K08640512 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45959 BRD-K08640512 NPC 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.09
46279 BRD-K08640512 PHH 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.19
46594 BRD-K08640512 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100039 BRD-K08640512 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).