CMap Candidate Details

Structure:
CMap ID: C05191
Pert ID: BRD-K08832567
Compound Name: naringenin
Targets: CYP19A1; ESR2
MoA: TRPV antagonist; Aromatase inhibitor
SMILES: Oc1ccc(cc1)[C@@H]1CC(=O)c2c(O)cc(O)cc2O1
InchiKey: FTVWIRXFELQLPI-ZDUSSCGKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95314 BRD-K08832567 A549 10 uM 48 h 0.28 1.16 0.35 0.23 0.82 0.1
95347 BRD-K08832567 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95390 BRD-K08832567 U2OS 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121149 BRD-K08832567 A375 0.04 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.72
121222 BRD-K08832567 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121250 BRD-K08832567 HELA 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121311 BRD-K08832567 PC3 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129295 BRD-K08832567 HT29 0.25 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.72
129369 BRD-K08832567 YAPC 2.22 uM 24 h 0.27 1.13 0.29 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).