CMap Candidate Details

Structure:
CMap ID: C00520
Pert ID: BRD-A20348246
Compound Name: chlormezanone
Targets: GABRA1
MoA: GABA receptor modulator
SMILES: CN1C(c2ccc(Cl)cc2)S(=O)(=O)CCC1=O
InchiKey: WEQAYVWKMWHEJO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127758 BRD-A20348246 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127802 BRD-A20348246 A549 0.04 uM 24 h -0.28 -1.15 0.44 0.27 0.97 0.35
127834 BRD-A20348246 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127887 BRD-A20348246 HEK293 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
127908 BRD-A20348246 HT29 0.04 uM 24 h -0.33 -1.39 1.09 0.33 1.16 0.91
127961 BRD-A20348246 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.38
128011 BRD-A20348246 MCF10A 0.04 uM 24 h -0.27 -1.14 0.42 0.0 0.0 0.0
135587 BRD-A20348246 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135679 BRD-A20348246 JURKAT 0.25 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.58
135706 BRD-A20348246 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135729 BRD-A20348246 PC3 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135750 BRD-A20348246 YAPC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).