CMap Candidate Details

Structure:
CMap ID: C05200
Pert ID: BRD-K08859203
Compound Name: DU-728
Targets: ITGA2B; ITGB3
MoA: Structural glycoprotein antagonist
SMILES: N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(O)=O
InchiKey: NNRFRJQMBSBXGO-CIUDSAMLSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121146 BRD-K08859203 A375 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.76 0.07
121183 BRD-K08859203 A549 1.11 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
121219 BRD-K08859203 HA1E 0.125 uM 24 h -0.27 -1.12 0.38 0.18 0.63 0.0
121266 BRD-K08859203 HELA 1.11 uM 3 h 0.0 0.0 0.0 -0.29 -0.99 0.5
121309 BRD-K08859203 PC3 10 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.29
121344 BRD-K08859203 YAPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129293 BRD-K08859203 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129328 BRD-K08859203 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.55
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).