CMap Candidate Details

Structure:
CMap ID: C05234
Pert ID: BRD-K08976401
Compound Name: azelaic-acid
Targets: TYR
MoA: Tyrosinase inhibitor
SMILES: OC(=O)CCCCCCCC(O)=O
InchiKey: BDJRBEYXGGNYIS-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121184 BRD-K08976401 A549 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121223 BRD-K08976401 HA1E 0.125 uM 24 h -0.18 -0.73 0.0 -0.3 -1.0 0.53
121251 BRD-K08976401 HELA 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121278 BRD-K08976401 HT29 0.125 uM 24 h 0.16 0.68 0.0 0.0 0.0 0.0
121312 BRD-K08976401 PC3 3.33 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
129243 BRD-K08976401 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129331 BRD-K08976401 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129370 BRD-K08976401 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).