CMap Candidate Details

Structure:
CMap ID: C00524
Pert ID: BRD-A20527803
Compound Name: IB-MECA
Targets: ADORA3
MoA: Adenosine receptor agonist
SMILES: CNC(=O)C1OC(C(O)C1O)n2cnc3c(NCc4cccc(I)c4)ncnc23
InchiKey: HUJXGQILHAUCCV-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1483 BRD-A20527803 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.2 -0.67 0.02
2030 BRD-A20527803 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2322 BRD-A20527803 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2526 BRD-A20527803 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41651 BRD-A20527803 A375 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.86 0.22
42183 BRD-A20527803 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42528 BRD-A20527803 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42836 BRD-A20527803 HT29 10 uM 6 h 0.24 1.01 0.11 -0.33 -1.13 0.97
43383 BRD-A20527803 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43700 BRD-A20527803 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95514 BRD-A20527803 A549 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
95585 BRD-A20527803 MCF??7.00 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
95631 BRD-A20527803 U2OS 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).