CMap Candidate Details
Structure:
| CMap ID: | C05269 |
| Pert ID: | BRD-K09078998 |
| Compound Name: | deforolimus |
| Targets: | MTOR |
| MoA: | MTOR inhibitor |
| SMILES: | CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)C=C(C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)C=CC=CC=C(C)[C@H](C[C@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@@H]1OP(C)(C)=O |
| InchiKey: | BUROJSBIWGDYCN-HSPIJORXSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 95336 | BRD-K09078998 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95463 | BRD-K09078998 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121148 | BRD-K09078998 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.08 | 0.78 |
| 121221 | BRD-K09078998 | HA1E | 1.11 uM | 24 h | 0.27 | 1.11 | 0.25 | 0.0 | 0.0 | 0.0 |
| 121310 | BRD-K09078998 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129272 | BRD-K09078998 | HELA | 0.74 uM | 3 h | -0.23 | -0.97 | 0.1 | -0.31 | -1.03 | 0.64 |
| 129294 | BRD-K09078998 | HT29 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.95 | 0.4 |
| 129330 | BRD-K09078998 | MCF??7.00 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129368 | BRD-K09078998 | YAPC | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.23 | 1.25 |