CMap Candidate Details

Structure:
CMap ID: C05342
Pert ID: BRD-K09372874
Compound Name: merimepodib
Targets: IMPDH1
MoA: IMPDH inhibitor
SMILES: COc1cc(NC(=O)Nc2cccc(CNC(=O)O[C@H]3CCOC3)c2)ccc1-c1cnco1
InchiKey: JBPUGFODGPKTDW-SFHVURJKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121189 BRD-K09372874 A549 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
129245 BRD-K09372874 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129254 BRD-K09372874 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129275 BRD-K09372874 HELA 2.22 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
129300 BRD-K09372874 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129335 BRD-K09372874 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129352 BRD-K09372874 PC3 2.22 uM 24 h 0.25 1.03 0.13 -0.34 -1.16 1.1
129374 BRD-K09372874 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).