CMap Candidate Details

Structure:
CMap ID: C05351
Pert ID: BRD-K09397065
Compound Name: SR-57227A
Targets: HTR3A
MoA: Serotonin receptor agonist
SMILES: NC1CCN(CC1)c1cccc(Cl)n1
InchiKey: WPVVMKYQOMJPIN-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3332 BRD-K09397065 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3723 BRD-K09397065 VCAP 10 uM 24 h 0.26 1.09 0.23 0.0 0.0 0.0
39297 BRD-K09397065 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39627 BRD-K09397065 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39945 BRD-K09397065 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40751 BRD-K09397065 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41050 BRD-K09397065 NPC 10 uM 24 h 0.2 0.82 0.0 -0.22 -0.75 0.06
41379 BRD-K09397065 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100047 BRD-K09397065 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
121152 BRD-K09397065 A375 3.33 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.77
121225 BRD-K09397065 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.49 -1.65 15.65
121279 BRD-K09397065 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121318 BRD-K09397065 PC3 0.37 uM 24 h 0.0 0.0 0.0 -0.44 -1.49 15.35
129263 BRD-K09397065 HELA 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129336 BRD-K09397065 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.37 1.31 1.59
129375 BRD-K09397065 YAPC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).