CMap Candidate Details

Structure:
CMap ID: C05365
Pert ID: BRD-K09426783
Compound Name: TAS-103
Targets: TOP1
MoA: Topoisomerase inhibitor
SMILES: CN(C)CCNc1nc2cc(O)ccc2c2-c3ccccc3C(=O)c12
InchiKey: ROWSTIYZUWEOMM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121187 BRD-K09426783 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121316 BRD-K09426783 PC3 0.37 uM 24 h 0.0 0.0 0.0 -0.44 -1.48 15.35
129244 BRD-K09426783 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129253 BRD-K09426783 HA1E 0.01 uM 24 h 0.0 0.0 0.0 -0.21 -0.71 0.03
129262 BRD-K09426783 HELA 0.03 uM 24 h 0.25 1.04 0.14 0.0 0.0 0.0
129298 BRD-K09426783 HT29 2.22 uM 24 h 0.33 1.38 0.97 0.0 0.0 0.0
129333 BRD-K09426783 MCF??7.00 0.25 uM 24 h -0.22 -0.93 0.07 -0.4 -1.34 1.85
129373 BRD-K09426783 YAPC 0.08 uM 24 h 0.27 1.11 0.26 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).