CMap Candidate Details

Structure:
CMap ID: C05420
Pert ID: BRD-K09602097
Compound Name: forskolin
Targets: ADCY2
MoA: Adenylyl cyclase activator
SMILES: CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]2(O)C(=O)C[C@@](C)(O[C@]12C)C=C
InchiKey: OHCQJHSOBUTRHG-KGGHGJDLSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5299 BRD-K09602097 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.79
5756 BRD-K09602097 HCC515 10 uM 6 h -0.2 -0.83 0.0 0.0 0.0 0.0
6403 BRD-K09602097 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44670 BRD-K09602097 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44849 BRD-K09602097 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45158 BRD-K09602097 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45964 BRD-K09602097 NPC 10 uM 24 h 0.23 0.96 0.07 0.33 1.16 0.9
46284 BRD-K09602097 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46600 BRD-K09602097 SKB 10 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
97696 BRD-K09602097 NKDBA 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121156 BRD-K09602097 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121281 BRD-K09602097 HT29 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.64
121351 BRD-K09602097 YAPC 10 uM 24 h 0.25 1.05 0.17 0.21 0.74 0.03
129265 BRD-K09602097 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129339 BRD-K09602097 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.25 0.9 0.22
129354 BRD-K09602097 PC3 2.22 uM 24 h 0.0 0.0 0.0 -0.38 -1.27 1.4
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).