CMap Candidate Details

Structure:
CMap ID: C05431
Pert ID: BRD-K09638361
Compound Name: IC-261
Targets: CSNK1E
MoA: Casein kinase inhibitor
SMILES: COc1cc(OC)c(/C=C2/C(=O)Nc3ccccc23)c(OC)c1
InchiKey: JBJYTZXCZDNOJW-JLHYYAGUSA-N
Compound Aliases: SA-63133

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1736 BRD-K09638361 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1881 BRD-K09638361 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2297 BRD-K09638361 PC3 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.3
41718 BRD-K09638361 A375 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.48
42055 BRD-K09638361 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42288 BRD-K09638361 ASC 10 uM 24 h 0.22 0.91 0.03 0.0 0.0 0.0
42621 BRD-K09638361 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42923 BRD-K09638361 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43157 BRD-K09638361 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43481 BRD-K09638361 NPC 10 uM 24 h 0.0 0.0 0.0 -0.41 -1.38 2.02
43786 BRD-K09638361 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90293 BRD-K09638361 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).